Dec 4, 2025
Howie and Harlan are joined by Sudhakar Nuti to discuss his work improving healthcare for homeless New Yorkers, as a street-medicine doctor and a population-health leader at NYC Health + Hospitals. Harlan reports on a proposed law that would cut off funding for U.S. scientists who collaborate with colleagues in China;...
Nov 27, 2025
Howie and Harlan are joined by Peter Hotez, a vaccine expert and an outspoken opponent of health misinformation, to discuss vaccine skepticism and the forces—from wellness influencers to HHS secretary Robert F. Kennedy Jr.—that amplify it. Harlan reports on research reinforcing the link between social media and...
Nov 20, 2025
Howie and Harlan discuss the outlook for U.S. healthcare spending over the next five years, the state of seasonal and avian flu, and an expensive AI-based cardiac test.
Show notes:
Life expectancy and expenditures
“How does U.S. life expectancy compare to other countries?”
ACOs and cost savings
Nov 13, 2025
Howie and Harlan are joined by Harvard internist Jerry Avorn to discuss his research on the pharmaceutical industry and his work promoting evidence-based prescribing. Harlan highlights new results from the American Heart Association meeting, including a one-time CRISPR-based therapy for high cholesterol; Howie reports...
Nov 6, 2025
Howie and Harlan are joined by cardiologist Ali Rahimi, the founder of ALYKA Health, which uses a personalized mobile app to help patients manage their heart health between doctor's visits. Harlan discusses new developments in GLP-1 obesity drugs, including untested microdose treatments; Howie reviews a landmark...